2020;41(2):145–151. Questions received by ECDC from the Member States regarding laboratory topics on SARS-CoV-2 by 21 February 2020. 69 April 1, 2020 U.S. Department of Health and Human Services Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report Early Release / Vol. A previous COVID-19 position statement pdf icon external icon issued by CSTE on April 5, 2020, included a case definition and made COVID-19 a nationally notifiable disease. At least two of the following symptoms: fever (measured or subjective), chills, rigors, myalgia, headache, sore throat, new olfactory and taste disorder(s), At least one of the following symptoms: cough, shortness of breath, or difficulty breathing. Coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in December 2019 in Wuhan, China, and has since spread rapidly, evolving into a full-blown pandemic. Wycliffe E. Wei; Zongbin Li; Calvin J. Chiew; Sarah E. Yong; Matthias P. Toh; Vernon J. Lee. In late December 2019, investigation of a cluster of pneumonia cases of unknown origin in Wuhan, China resulted in identification of a novel coronavirus. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) in China. Clinical or radiographic evidence of pneumonia, OR 2. Hiroshi Nishiura, Natalie M. Linton, Andrei R. Akhmetzhanov PII: S1201-9712(20)30119-3 DOI: https://doi.org/10.1016/j.ijid.2020.02.060 Reference: IJID 4006 To appear in: International Journal of Infectious Diseases, Accepted Date: 27 February 2020, Presymptomatic Transmission of SARS-CoV-2 — Singapore, January 23–March 16, 2020. Travel to or residence in an area with sustained, ongoing community transmission of SARS-CoV-2. Clinical or radiographic evidence of pneumonia. At least one of the following two epidemiological links: The term “suspect cases” which addressed individuals who should be tested for COVID-19 is no longer used. The testing guidance will be regularly updated, however, those with symptoms who meet the higher index of … A notifiable disease or condition is one for which regular, frequent, and timely information regarding individual cases is considered necessary to prevent and control the disease or condition. Epidemiological reports from the field are demonstrating a growing importance of presymptomatic and asymptomatic infections from two lines of evidence: the serial interval of COVID-19 appears to be close to or shorter than its median incubation period and clusters linked to presymptomatic and asymptomatic index cases2, 3. A case definition is a set of standard criteria for classifying whether a person has a particular disease, syndrome, or other health condition. Everyone is assumed to be susceptible, although there may be risk factors that increase an individual’s illness severity. Probable Case A. Most cases in China occurred in households and in Washington, for example, a significant cluster was associated with a long-term care facility. Severe respiratory illness with at least one of the following: Laboratory evidence using a method approved or authorized by the U.S. Food and Drug Administration (FDA) or designated authority: *Serologic methods for diagnosis are currently being defined. The case definition document identifies those with a higher risk of having COVID-19 and outlines the reporting and self-isolation requirements for those with symptoms who meet the Higher Index of Suspicion (HIS) criteria. Laboratory support (for primary/and or confirmatory testing) by Coronavirus specialised laboratories in the EU. For this reason, some items on this page will be unavailable. Not applicable (N/A) until more virologic data are available. Close contact** with a confirmed or probable case of COVID-19 disease; linkage to a confirmed case of COVID-19 disease. Cases of COVID-19 in China and the initial U.S. cases in early March 2020 have been clustered. Centers for Disease Control and Prevention, Office of Public Health Scientific Services (OPHSS), Center for Surveillance, Epidemiology, and Laboratory Services (CSELS), Division of Health Informatics and Surveillance (DHIS), U.S. Department of Health & Human Services. Zhonghua Liu Xing Bing Xue Za Zhi. Ongoing surveillance of illness, risk factors, and epidemiologic linkage is needed to characterize the disease transmission in the United States, and to inform intervention and mitigation strategies. 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